Biochemical Reagents
Medchemexpress LLC Beta-D-glucuronide-pNP-carbonate | 894095-98-8 | MFCD31715405 | >96.0% | 913.83 g/mol | C45H43N3O18 | 50 MG
β-D-glucuronide-pNP-carbonate is a glycosidase-cleavable antibody-drug conjugate (ADC) linker that contains a para-nitrophenyl carbonate reactive handle and a β-D-glucuronide cleavable trigger. It is supplied as a solid for research use and is designed to release payloads upon enzymatic cleavage by glucuronidase.
- Glycosidase-cleavable linker for targeted payload release.
- Para-nitrophenyl carbonate reactive handle for payload attachment.
- Solid form suitable for standard laboratory handling.
- Available in small research-scale quantities for synthesis work.
- Intended for research use only; not for clinical or human use.
Medchemexpress LLC Chmfl-pi4k-127 | 2377604-81-2 | 99.9% | 402.85 g/mol | C18H15ClN4O3S | 10 MG
CHMFL-PI4K-127 is a potent, selective Plasmodium falciparum phosphatidylinositol 4-kinase (PfPI4K) inhibitor provided for research use. It exhibits sub-nanomolar enzymatic potency and cellular antimalarial activity, and is supplied at high chemical purity suitable for in vitro and in vivo studies.
- Potent PfPI4K inhibition (IC50 ~0.9 nM).
- Demonstrated cellular antimalarial activity (EC50 ~25.1 nM).
- High chemical purity for reliable experimental results (>99.9%).
- Available in research-scale quantities for assay development.
- Soluble in DMSO for standard compound handling and dosing.
AdipoGen 3-oxo-C11-L-HSL
Chemical. CAS 216596-70-2. Formula C15H25NO4. MW 283.4. Synthetic. N-3-Oxoundecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
AdipoGen 3-Oxo-C9-L-HSL
Chemical. CAS 441350-70-5. Formula C13H21NO4. MW 255.31. N-3-Oxononanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Medchemexpress LLC Sesamolin | 526-07-8 | 99.8% | 370.35 | C20H18O7 | 10 MG
Sesamolin is a lignan isolated from Sesamum indicum with antioxidative and neuroprotective activity. It inhibits lipid peroxidation and suppresses MAPK cascade signaling by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3; oral activity has been reported. The compound is supplied as a solid and as DMSO solutions and is typically provided at high purity for research use.
- Antioxidative activity
- Inhibits lipid peroxidation
- Suppresses JNK and p38 MAPK phosphorylation
- Reduces caspase-3 activation
- Reported oral bioactivity
- High purity (99.78%)
- Available as solid and DMSO solution, including 10 mg solid
Medchemexpress LLC D-Nmappd | 35922-06-6 | MFCD08062172 | 99.7% | 422.6 g/mol | C23H38N2O5 | 25MG
D-NMAPPD ((1R,2R)-B13) is a research-grade small-molecule acid ceramidase inhibitor that modulates NMDA receptor properties by enhancing endogenous ceramide production. It is used in biochemical and neurological research and has been reported to show anticancer activity in experimental studies. The compound is supplied in milligram-scale quantities with high reported purity suitable for laboratory applications.
- Inhibits acid ceramidase activity.
- Modulates NMDA receptor properties by enhancing endogenous ceramide production.
- Reported anticancer activity in experimental studies.
- High purity (~99.7%) suitable for research use.
- Molecular formula C23H38N2O5; molecular weight 422.6 g/mol.
- Available in milligram-scale package sizes for laboratory experiments.
Medchemexpress LLC Integrin alpha 8 bet 50ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 50 MG
D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid, intended for research and analytical applications. It is a major component of many anti-inflammatory proteoglycans, promoting embryonic development and inhibiting cell aggregation. This compound and its derivative glucurono-lactone can also serve as liver detoxifiers for human health prevention, and its derivatives possess anti-tumor activity.
- Analytical standard for research and analytical applications
- Major component of many anti-inflammatory proteoglycans
- Promotes embryonic development and inhibits cell aggregation
- Can serve as a liver detoxifier
- Derivatives possess anti-tumor activity
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Heparin Lithium salt | 9045-22-1 | 500 MG
Heparin Lithium salt is an anticoagulant that binds reversibly to antithrombin III (ATIII) and significantly inhibits exosome-cell interactions.
- Anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Significantly inhibits exosome-cell interactions
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 100 MG
Sodium zirconium cyclosilicate is an inorganic, microporous zirconium silicate compound used as a selective cation-exchange reagent that binds potassium ions for biomedical and kidney disease research.
- Selectively binds potassium ions for removal in vitro or preclinical studies.
- Inorganic, non-absorbed microporous structure suitable for research applications.
- Available in multiple small-scale sizes for laboratory use.
- Supplied as a solid reagent with specified purity for experimental reproducibility.
Medchemexpress LLC D-Glucuronic acid | 99.9% | 240.09 g·mol⁻¹ | 13C6H11NaO8 | 10 MG
13C6-labeled D-glucuronic acid sodium salt monohydrate provided as a stable-isotope internal standard for metabolomics and biochemical research. The material is the sodium salt monohydrate of D-glucuronic acid, isotopically labeled on all six carbons (13C6), and supplied as a high-purity dry solid.
- 13C6 isotopic labeling for tracer and internal standard use.
- High purity (HPLC) - 99.9%.
- Molecular weight 240.09 g·mol⁻¹ and formula 13C6H11NaO8.
- Suitable for LC-MS and metabolomics workflows as a standard or tracer.
- Supplied as a stable dry solid for controlled storage.
Medchemexpress LLC IL-1RA/IL-1F3 Porci 50ug | 50ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin alpha V beta 6 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His) has molecular weight of 130 95 KDa respectively
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | MFCD32689543 | 96.4% | 897.90 | C42H47N3O17S | 25 MG
MAC glucuronide linker-1 is a cleavable antibody-drug conjugate (ADC) linker intended for research use, designed to release payloads through glucuronide cleavage under target conditions.
- Cleavable glucuronide-based linker for antibody-drug conjugates.
- Intended for research use only.
- CAS number 2222981-71-5.
- Purity 96.36%.
- Molecular weight 897.90.
- Chemical formula C42H47N3O17S.
- Appearance white to off-white solid.
- Storage: store under nitrogen; in solvent, -80°C for 6 months and -20°C for 1 month.